Eczema (Atopic Dermatitis)
Topical Effect: cooling / itch-relieving / anti-inflamation.
AsterCura™
Products known as cosmeceuticals have both therapeutic (medical) and aesthetic (beauty) properties. To improve and treat various skin diseases, these products may have bioactive components. One of the bioactive components that falls under the category of cosmeceuticals are secretomes. These secretomes consist of various useful cytokines that are extracted and purified under AsterCura from a conditioned culture medium for cosmeceutical applications.
Various research analyses have been carried out, such as proteomic analysis, to evaluate the cytokines' profile, and in vitro skin testing has been carried out to evaluate the efficacy and safety of cytokines. Encapsulation and formulation of cytokines using in-house techniques are available for better encapsulation, performance and stability of cosmeceuticals, for in vivo clinical trials.
A group of proteins called secretomes are excreted by donor cells and are capable of signaling recipient cells to alter their biological activities in order to control skin repair and the regeneration of damaged cells. Exosomes, soluble cytokines, growth factors, extracellular matrix proteins, and many other substances are included in secretomes.
They are a large class of bio-signaling proteins, peptides, or glycoproteins that are excreted by particular immune cells and are essential in regulating the growth and activity of other immune system cells and blood cells. The term "cytokine" is derived from a combination of two Greek words "cyto" meaning cell and "kinos" meaning movement.
Related receptors are combined to produce cytokines' effects. This is done to control immunological response, cell differentiation, and growth. In order to cure numerous skin disorders like aging, UV damage, dehydration, and scarring, cytokines can be employed as cosmeceuticals.
